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Table 2 Univariate analyses and adjusted proportional hazard regression analyses of QOL

From: Prognostic value of quality of life score in disease-free survivors of surgically-treated lung cancer

Variable No. of deaths/No. of participants Crude HR 95 % CI aHRa 95 % CI
EORTC-QCQ -C30 Physical functioning >33.33 87/783 1    1   
   ≤33.33 9/26 3.71 1.87 7.36 3.44 1.72 6.88
  Role functioning >33.33 89/782 1    1   
   ≤33.33 7/27 2.51 1.16 5.41 2.14 0.99 4.65
  Emotional functioning >33.33 92/792 1    1   
   ≤33.33 4/17 2.12 0.78 5.77 2.59 0.94 7.14
  Cognitive functioning >33.33 94/793 1    1   
   ≤33.33 2/16 1.08 0.27 4.37 0.95 0.23 3.90
  Social functioning >33.33 91/786 1    1   
   ≤33.33 5/23 1.99 0.81 4.88 1.56 0.63 3.88
  General health status >33.33 89/770 1    1   
   ≤33.33 7/39 1.62 0.75 3.49 1.35 0.62 2.93
  Fatigue <66.66 83/720 1    1   
   ≥66.66 13/89 1.30 0.72 2.33 1.24 0.69 2.24
  Nausea & vomiting <66.66 94/790 1    1   
   ≥66.66 2/19 0.91 0.23 3.73 0.82 0.20 3.33
  Pain <66.66 87/752 1    1   
   ≥66.66 9/57 1.41 0.71 2.80 1.28 0.61 2.66
  Dyspnea <66.66 53/591 1    1   
   ≥66.66 43/218 2.33 1.56 3.48 1.96 1.30 2.95
  Insomnia <66.66 79/689 1    1   
   ≥66.66 17/120 1.24 0.73 2.09 1.27 0.75 2.16
  Appetite loss <66.66 76/717 1    1   
   ≥66.66 20/92 2.20 1.35 3.61 1.68 1.00 2.82
  Constipation <66.66 87/746 1    1   
   ≥66.66 9/63 1.24 0.63 2.47 1.13 0.57 2.27
  Diarrhea <66.66 88/773 1    1   
   ≥66.66 8/36 2.13 1.03 4.39 2.11 1.01 4.40
  Financial difficulties <66.66 77/686 1    1   
   ≥66.66 19/123 1.39 0.84 2.30 1.14 0.68 1.89
EORTC-QCQ -LC13 Dyspnea <66.66 77/733 1    1   
   ≥66.66 19/76 2.62 1.59 4.33 2.26 1.36 3.76
  Coughing <66.66 77/726 1    1   
   ≥66.66 19/83 2.35 1.42 3.88 1.92 1.15 3.20
  Hemoptysis <66.66 95/803 1    1   
   ≥66.66 1/6 1.35 0.19 9.67 0.82 0.11 5.94
  Sore mouth <66.66 90/782 1    1   
   ≥66.66 6/26 2.15 0.94 4.91 1.83 0.80 4.19
  Dysphagia <66.66 90/783 1    1   
   ≥66.66 6/26 2.18 0.96 4.99 1.62 0.70 3.74
  Peripheral neuropathy <66.66 84/725 1    1   
   ≥66.66 12/84 1.28 0.70 2.35 1.29 0.70 2.37
  Alopecia <66.66 89/756 1    1   
   ≥66.66 7/52 1.17 0.54 2.53 1.26 0.58 2.74
  Pain in chest <66.66 80/727 1    1   
   ≥66.66 16/82 1.85 1.08 3.16 1.70 0.98 2.95
  Pain in arm or shoulder <66.66 82/699 1    1   
   ≥66.66 14/110 1.09 0.62 1.93 1.22 0.69 2.15
  Pain in other body parts <66.66 83/726 1    1   
   ≥66.66 12/82 1.32 0.72 2.43 1.44 0.78 2.65
  1. Abbreviations: HR hazard ratio, aHR adjusted hazard ratio, CI confidence interval
  2. aEach of the multiple proportional hazard regression analysis was adjusted for age, sex, stage, BMI at the time of survey, and MET
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