Skip to main content

Advertisement

Table 5 Comparison of biological processes associated with each gene signature

From: The effects of lymph node status on predicting outcome in ER+ /HER2- tamoxifen treated breast cancer patients using gene signatures

   Signature
  Biological Pathway Ellen Oncotype DX Prosigna
Common Gene expression 15 2 5
Proliferation 11 4 15
Immune response 8 3 1
Cell migration 7 4 9
Cell cycle 1 4 12
PTM and trafficking 1 2 4
Unique Epigenetics 4 0 0
Angiogenesis 2 0 0
DNA repair 0 0 4
DNA replication 0 0 3
Other Apoptosis 7 0 1
Metabolism 5 0 2
Stress response 5 0 2
Differentiation 2 0 2
Cytoskeleton 1 0 5
Intracellular signalling 0 3 6
Survival 0 2 2
Drug metabolism 0 1 1