Table 5 Comparison of biological processes associated with each gene signature
| Â | Â | Signature | ||
|---|---|---|---|---|
| Â | Biological Pathway | Ellen | Oncotype DX | Prosigna |
Common | Gene expression | 15 | 2 | 5 |
Proliferation | 11 | 4 | 15 | |
Immune response | 8 | 3 | 1 | |
Cell migration | 7 | 4 | 9 | |
Cell cycle | 1 | 4 | 12 | |
PTM and trafficking | 1 | 2 | 4 | |
Unique | Epigenetics | 4 | 0 | 0 |
Angiogenesis | 2 | 0 | 0 | |
DNA repair | 0 | 0 | 4 | |
DNA replication | 0 | 0 | 3 | |
Other | Apoptosis | 7 | 0 | 1 |
Metabolism | 5 | 0 | 2 | |
Stress response | 5 | 0 | 2 | |
Differentiation | 2 | 0 | 2 | |
Cytoskeleton | 1 | 0 | 5 | |
Intracellular signalling | 0 | 3 | 6 | |
Survival | 0 | 2 | 2 | |
Drug metabolism | 0 | 1 | 1 | |