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Fig. 2 | BMC Cancer

Fig. 2

From: 5-lipoxygenase mediates docosahexaenoyl ethanolamide and N-arachidonoyl-L-alanine-induced reactive oxygen species production and inhibition of proliferation of head and neck squamous cell carcinoma cells

Fig. 2

The anti-cancer action of DHEA and NALA occurs at an intracellular location. Plasmids (1 μg) expressing LacZ and FAAH were transfected into (a) SNU-1041 and (b) SNU-1076 (LacZ expressing plasmid was used for controls). Thirthy-six hours later cells were treated with the indicated concentrations (μM) of DHEA or NALA. At additional 48 h, cells were subjected to cell proliferation assay. Results are expressed as a percentage relative to control (% of control). P values are based on a comparison with DHEA-treated group and NALA-treated group in LacZ (*P < 0.001, #P < 0.005)

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