Table 3 Association of clinicopathological parameters and β-catenin and PROX1 expression combined
From: PROX1 and β-catenin are prognostic markers in pancreatic ductal adenocarcinoma
Low | Moderate | High | ||
|---|---|---|---|---|
n (%) | 38 (25.0) | 56 (36.8) | 58 (38.2) | p-value |
Age, years | ||||
< 65 | 21 (55.3) | 32 (57.1) | 23 (39.7) | 0.121 |
≥ 65 | 17 (44.7) | 24 (42.9) | 35 (60.3) | |
Gender | ||||
Male | 23 (60.5) | 31 (55.4) | 30 (51.7) | 0.409 |
Female | 15 (39.5) | 25 (44.6) | 28 (48.3) | |
T | ||||
1 | 2 (5.3) | 4 (7.1) | 5 (8.6) | 0.343 |
2 | 10 (26.3) | 12 (21.4) | 18 (31.0) | |
3 | 25 (65.8) | 39 (69.6) | 34 (58.6) | |
4 | 1 (2.6) | 1 (1.8) | 1 (1.7) | |
N | ||||
0 | 10 (26.3) | 17 (30.4) | 20 (34.5) | 0.436 |
1 | 28 (73.7) | 39 (69.6) | 38 (65.5) | |
Stage (WHO) | ||||
IA | 2 (5.3) | 3 (5.4) | 4 (6.9) | 0.412 |
IB | 4 (10.5) | 6 (10.7) | 8 (13.8) | |
IIA | 4 (10.5) | 7 (12.5) | 8 (13.8) | |
IIB | 27 (71.1) | 39 (69.6) | 37 (63.8) | |
III | 1 (2.6) | 1 (1.8) | 1 (1.7) | |
Lymph node ratio | ||||
< 20 % | 29 (76.3) | 38 (67.9) | 49 (87.5) | 0.138 |
≥ 20 % | 9 (23.7) | 18 (32.1) | 7 (12.5) | |
Missing | 2 | |||
Grade | ||||
1 | 4 (12.5) | 7 (14.0) | 11 (22.4) | 0.059 |
2 | 20 (62.5) | 36 (72.0) | 33 (67.3) | |
3 | 8 (25.0) | 7 (14.0) | 5 (10.2) | |
Missing | 6 | 6 | 9 | |
Perineural invasion | ||||
Yes | 25 (73.5) | 32 (76.2) | 42 (80.8) | 0.438 |
No | 9 (26.5) | 10 (23.8) | 10 (19.2) | |
Missing | 4 | 14 | 6 | |
Perivascular invasion | ||||
Yes | 13 (38.2) | 17 (42.5) | 13 (26.5) | 0.247 |
No | 21 (61.8) | 23 (57.5) | 36 (73.5) | |
Missing | 4 | 16 | 9 | |