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Table 3 Association of clinicopathological parameters and β-catenin and PROX1 expression combined

From: PROX1 and β-catenin are prognostic markers in pancreatic ductal adenocarcinoma

  Low Moderate High  
n (%) 38 (25.0) 56 (36.8) 58 (38.2) p-value
Age, years     
  < 65 21 (55.3) 32 (57.1) 23 (39.7) 0.121
  ≥ 65 17 (44.7) 24 (42.9) 35 (60.3)  
Gender     
 Male 23 (60.5) 31 (55.4) 30 (51.7) 0.409
 Female 15 (39.5) 25 (44.6) 28 (48.3)  
T     
 1 2 (5.3) 4 (7.1) 5 (8.6) 0.343
 2 10 (26.3) 12 (21.4) 18 (31.0)  
 3 25 (65.8) 39 (69.6) 34 (58.6)  
 4 1 (2.6) 1 (1.8) 1 (1.7)  
N     
 0 10 (26.3) 17 (30.4) 20 (34.5) 0.436
 1 28 (73.7) 39 (69.6) 38 (65.5)  
Stage (WHO)     
 IA 2 (5.3) 3 (5.4) 4 (6.9) 0.412
 IB 4 (10.5) 6 (10.7) 8 (13.8)  
 IIA 4 (10.5) 7 (12.5) 8 (13.8)  
 IIB 27 (71.1) 39 (69.6) 37 (63.8)  
 III 1 (2.6) 1 (1.8) 1 (1.7)  
Lymph node ratio
  < 20 % 29 (76.3) 38 (67.9) 49 (87.5) 0.138
  ≥ 20 % 9 (23.7) 18 (32.1) 7 (12.5)  
 Missing    2  
Grade     
 1 4 (12.5) 7 (14.0) 11 (22.4) 0.059
 2 20 (62.5) 36 (72.0) 33 (67.3)  
 3 8 (25.0) 7 (14.0) 5 (10.2)  
 Missing 6 6 9  
Perineural invasion
 Yes 25 (73.5) 32 (76.2) 42 (80.8) 0.438
 No 9 (26.5) 10 (23.8) 10 (19.2)  
 Missing 4 14 6  
Perivascular invasion
 Yes 13 (38.2) 17 (42.5) 13 (26.5) 0.247
 No 21 (61.8) 23 (57.5) 36 (73.5)  
 Missing 4 16 9  
  1. Linear-by-linear association test was used here
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