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Fig. 2 | BMC Cancer

Fig. 2

From: The triptolide derivative MRx102 inhibits Wnt pathway activation and has potent anti-tumor effects in lung cancer

Fig. 2

MRx102 inhibits lung cancer tumor formation comparable to triptolide. a Mice were subcutaneously injected with H460 cells. Representative tumors from NSG mice that were treated with either PBS (control), 0.5 mg/kg triptolide, or 1 mg/kg MRx102. b Quantification of tumor volume from mice in (A). c Quantification of tumor weight from mice in (A). No less than 7 mice were used and p-values were determined using one-way Anova with a Tukey post test. * and ** represent p values of < .05 and <0.01, respectively, and are derived from a comparison between the control and treated groups

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