Skip to main content

Table 1 Subtyping algorithm of breast cancer specimens according to St Gallen consensus 2013

From: Technical validation of an RT-qPCR in vitro diagnostic test system for the determination of breast cancer molecular subtypes by quantification of ERBB2, ESR1, PGR and MKI67 mRNA levels from formalin-fixed paraffin-embedded breast tumor specimens

ERBB2 ESR1 PGR MKI67 St Gallen 2013 equivalent
pos pos pos pos Luminal B-like (HER2 positive)
pos pos pos neg Luminal B-like (HER2 positive)
pos pos neg pos Luminal B-like (HER2 positive)
pos pos neg neg Luminal B-like (HER2 positive)
pos neg pos pos Not defined
pos neg pos neg Not defined
pos neg neg pos HER2 positive (non-luminal)
pos neg neg neg HER2 positive (non-luminal)
neg pos pos pos Luminal B-like (HER2 negative)
neg pos pos neg Luminal A-like
neg pos neg pos Luminal B-like (HER2 negative)
neg pos neg neg Luminal B-like (HER2 negative)
neg neg pos pos Not defined
neg neg pos neg Not defined
neg neg neg pos Triple negative (ductal)
neg neg neg neg Triple negative (ductal)