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Table 1 Melanoma tumor mass after treatment with different regimens

From: INFα-2b inhibitory effects on CD4+CD25+FOXP3+ regulatory T cells in the tumor microenvironment of C57BL/6 J mice with melanoma xenografts

Groups

Control

Radiotherapy

Chemotherapy

Chemoradio-

INFα

Treatment

None

6 MeV X-ray 500 cGy

DTIC 40 mg/kg,D9-15

X-ray + DTIC

IFNα-2b 10000U D7,9,11,13,15

Number of mice

6

6

6

6

6

Weight of mass (g)

3.70 ± 0.94

3.14 ± 0.90

2.18 ± 0.77

2.15 ± 1.03

3.21 ± 1.86

p value

 

0.366

0.024

0.039

0.617

Volume of mass (cm3)

4.56 ± 0.94

2.60 ± 0.68

2.66 ± 1.18

2.10 ± 1.12

2.44 ± 1.37

p value

 

0.005

0.023

0.006

0.021

Inhibition rate (%)

N/A

15.1

40.91

41.83

13.15