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Fig. 4 | BMC Cancer

Fig. 4

From: INFα-2b inhibitory effects on CD4+CD25+FOXP3+ regulatory T cells in the tumor microenvironment of C57BL/6 J mice with melanoma xenografts

Fig. 4

Immunohistochemistry and positive scores of TGFβ and IL-10 in the tumor microenvironment. a. Immunohistochemistry graphs of tumor xenografts in C57BL/6 J mice, post treatment. Extensive expression of TGFβ and IL-10 could be detected in the area surrounding the melanoma cells post radiotherapy and chemotherapy, while IFNα had little effect on the expression of TGFβ and IL-10. b and c Immunohistochemistry positive scores of TGFβ and IL-10. * indicates P < 0.05, ** indicates P < 0.01 and *** indicates P < 0.001 compared with the control group

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BMC Cancer

ISSN: 1471-2407

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