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Fig. 1 | BMC Cancer

Fig. 1

From: INFα-2b inhibitory effects on CD4+CD25+FOXP3+ regulatory T cells in the tumor microenvironment of C57BL/6 J mice with melanoma xenografts

Fig. 1

Changes in the tumors after treatment with different therapies. a C57BL/6 J mice and excised tumors from each group. b Volumes of the tumors treated with radiotherapy (RT), chemotherapy (CT), radiochemotherapy (RCT) and IFNα were significantly smaller than those of the control group, p < 0.05. V = 4/3πabc, a. major radius, b. minor radius, c. radius perpendicular to minor axis, measured by ultrasound. c Excised tumors were weighed using an analytical balance. Tumor weights were reduced significantly in the CT and RCT groups, while only mildly reduced in the RT and IFNα groups. d. Tumor inhibition rate ((Wcontrol-Wtreatment)/Wcontrol × 100 %) after treatment based on the tumor mass

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