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Table 3 Correlation of IL-22 concentrations in lavage with distinct cell populations in the lavage samples of patients with pneumonia or lung cancer. Not all lavage cell populations were measured in all patients. Correlation was analyzed using Spearman’s rank-based correlation test after setting all IL-22 values <15 to 0

From: Interleukin-22 is elevated in lavage from patients with lung cancer and other pulmonary diseases

Correlation of IL-22 in lavage with cell populations in lavage

Subgroup size (n)

p-value for correlation

Patients with Lung Cancer

 Correlation of IL-22 in BL with BL Lymphocytes

9

0.66

 Correlation of IL-22 in BL with BL Macrophages

9

0.59

 Correlation of IL-22 in BL with BL Neutrophils

9

0.53

 Correlation of IL-22 in BL with BL Eosinophils

9

0.95

 Correlation of IL-22 in BL with BL CD4/CD8 ratio

4

0.051

Patients with Pneumonia

 Correlation of IL-22 in BL with BL Lymphocytes

32

0.5

 Correlation of IL-22 in BL with BL Macrophages

32

0.98

 Correlation of IL-22 in BL with BL Neutrophils

26

0.86

 Correlation of IL-22 in BL with Eosinophils

26

0.98

 Correlation of IL-22 in BL with BL CD4/CD8 ratio

34

0.65