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Table 3 Correlation of IL-22 concentrations in lavage with distinct cell populations in the lavage samples of patients with pneumonia or lung cancer. Not all lavage cell populations were measured in all patients. Correlation was analyzed using Spearman’s rank-based correlation test after setting all IL-22 values <15 to 0

From: Interleukin-22 is elevated in lavage from patients with lung cancer and other pulmonary diseases

Correlation of IL-22 in lavage with cell populations in lavage Subgroup size (n) p-value for correlation
Patients with Lung Cancer
 Correlation of IL-22 in BL with BL Lymphocytes 9 0.66
 Correlation of IL-22 in BL with BL Macrophages 9 0.59
 Correlation of IL-22 in BL with BL Neutrophils 9 0.53
 Correlation of IL-22 in BL with BL Eosinophils 9 0.95
 Correlation of IL-22 in BL with BL CD4/CD8 ratio 4 0.051
Patients with Pneumonia
 Correlation of IL-22 in BL with BL Lymphocytes 32 0.5
 Correlation of IL-22 in BL with BL Macrophages 32 0.98
 Correlation of IL-22 in BL with BL Neutrophils 26 0.86
 Correlation of IL-22 in BL with Eosinophils 26 0.98
 Correlation of IL-22 in BL with BL CD4/CD8 ratio 34 0.65