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Table 2 Correlation of IL-22 concentrations in lavage with systemic inflammation parameters in samples from patients with pneumonia or lung cancer. Leucocyte subpopulations were not measured in all patients. Correlation was analyzed using Spearman’s rank-based correlation test after setting all IL-22 values <15 to 0

From: Interleukin-22 is elevated in lavage from patients with lung cancer and other pulmonary diseases

Correlation of IL-22 in lavage with markers of systemic inflammation Subgroup size (n) p-value for correlation
Patients with Lung Cancer
 Correlation of IL-22 in BL with CRP 16 0.19
 Correlation of IL-22 in BL with Leucocytes 16 0.33
 Correlation of IL-22 in BL with Lymphocytes 6 0.28
 Correlation of IL-22 in BL with Neutrophils 6 0.35
Patients with Pneumonia
 Correlation of IL-22 in BL with CRP 30 0.16
 Correlation of IL-22 in BL with Leucocytes 30 0.21
 Correlation of IL-22 in BL with Lymphocytes 18 0.77
 Correlation of IL-22 in BL with Neutrophils 19 0.30