Fig. 2

MiR-944 suppresses cell migration and invasion. (a and e) MTT cell viability assays of MDA-MB-231 (a) and MCF-7 (e) cells transfected with miR-944 precursor (50 nM to 200 nM). (b and f) Scratch/wound-healing assays of MDA-MB-231 (b) and MCF-7 (f) cells monolayers treated with miR-944 precursor (50 nM). (c and g) Transwell assays of MDA-MB-231 (c) and MCF-7 (g) cells transfected with miR-944 precursor (50 nM). (d) Matrigel invasion assays of MDA-MB-231 cells transfected with miR-944 precursor (50 nM). Non-transfected cells were used as controls. Bars represent the mean of three independent experiments performed three times ± S.D. Asterisks indicate p < 0.05