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Fig. 1 | BMC Cancer

Fig. 1

From: Involvement of DNMT 3B promotes epithelial-mesenchymal transition and gene expression profile of invasive head and neck squamous cell carcinomas cell lines

Fig. 1

Morphology changed and EMT-related transcription factors expression in invasive subpopulation of A253. Parental A253 (a with low density: 4 × 103cells per mm2 and b with high dansity: 1 × 104 cells per mm2) cells were photographed at 100 X magnificence. Invasive subpopulation of A253-3 (c) and A253-5 (d) (with hight dansity: 1 × 104 cells per mm2) had more spindle-shape cells (indicated by arrows). e Three EMT-related transcription factors (Snail, Slug, and Twist) were evaluated its mRNA expression by Q-PCR. Data was expressed as fold change to A253-0. ** indicated p < 0.01 and *** indicated p < 0.001 as compared with A253-0

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BMC Cancer

ISSN: 1471-2407

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