Skip to main content

Advertisement

Table 3 Univariate and multivariate analysis of overall survival

From: Metalloproteases meprin-ɑ (MEP1A) is a prognostic biomarker and promotes proliferation and invasion of colorectal cancer

  Univariate analysis Multivariate analysis
HR (95 % CI) P value HR (95 % CI) P value
Age     
 <65 1    
 ≥65 1.350 (0.706-2.581) 0.364   
Gender     
 Male 1    
 Female 0.910 (0.503-1.648) 0.756   
Location     
 Right 1   1  
 Others 0.470 (0.259-0.852) 0.013* 0.666 (0.335-1.323) 0.246
Tumor size (cm)     
 <5 1    
 ≥5 1.801 (0.993-3.267) 0.053   
AJCC stage     
 I + II 1   1  
 III + IV 3.106 (1.701-5.671) <0.001* 1.335 (0.305-5.842) 0.701
T stage     
 T1 + T2 1    
 T3 + T4 1.662 (0.514-5.370) 0.396   
N stage     
 N0 1   1  
 N1 + N2 3.106 (1.701-5.671) <0.001* 2.129 (0.468-9.686) 0.328
M stage     
 M0 1   1  
 M1 10.801 (2.448-47.658) 0.002* 14.382 (1.059-195.249) 0.045*
Differentiation     
 Well + Moderate 1    
 Poor 2.026 (0.627-6.548) 0.238   
Vascular invasion     
 No 1   1  
 Yes 6.188 (2.093-18.295) <0.001* 1.190 (0.264-5.366) 0.821
MEP1A     
 Low 1   1  
 High 5.977 (2.651-13.478) <0.001* 3.643 (0.305-5.842) 0.007*
E-cadherin     
 Low 1   1  
 High 0.425 (0.215-0.842) 0.014* 0.605 (0.252-1.453) 0.261
  1. Key: *indicates P < 0.05