Table 3 Univariate and multivariate analysis of overall survival

Age

 <65

1

 ≥65

1.350 (0.706-2.581)

0.364

Gender

 Male

1

 Female

0.910 (0.503-1.648)

0.756

Location

 Right

1

1

 Others

0.470 (0.259-0.852)

0.013*

0.666 (0.335-1.323)

0.246

Tumor size (cm)

 <5

1

 ≥5

1.801 (0.993-3.267)

0.053

AJCC stage

 I + II

1

1

 III + IV

3.106 (1.701-5.671)

<0.001*

1.335 (0.305-5.842)

0.701

T stage

 T1 + T2

1

 T3 + T4

1.662 (0.514-5.370)

0.396

N stage

 N0

1

1

 N1 + N2

3.106 (1.701-5.671)

<0.001*

2.129 (0.468-9.686)

0.328

M stage

 M0

1

1

 M1

10.801 (2.448-47.658)

0.002*

14.382 (1.059-195.249)

0.045*

Differentiation

 Well + Moderate

1

 Poor

2.026 (0.627-6.548)

0.238

Vascular invasion

 No

1

1

 Yes

6.188 (2.093-18.295)

<0.001*

1.190 (0.264-5.366)

0.821

MEP1A

 Low

1

1

 High

5.977 (2.651-13.478)

<0.001*

3.643 (0.305-5.842)

0.007*

E-cadherin

 Low

1

1

 High

0.425 (0.215-0.842)

0.014*

0.605 (0.252-1.453)

0.261