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Table 1 Relationship between clinicopathologic parameters and MEP1A or E-cadherin protein expression (n = 88)

From: Metalloproteases meprin-ɑ (MEP1A) is a prognostic biomarker and promotes proliferation and invasion of colorectal cancer

Parameters Total MEP1A P E-cadherin P
Low37 High51 Low55 High33
Age        
 <65 31 13 18   16 15  
 ≥65 57 24 33 0.988a 39 18 0.120a
Gender        
 Male 46 18 28   29 17  
 Female 42 19 23 0.562a 26 16 0.912a
Location        
 Right 37 15 22   21 16  
 Others 51 22 29 0.808a 34 17 0.343a
Tumor size (cm)        
 <5 47 25 22   31 16  
 ≥5 41 12 29 0.023*a 24 17 0.473a
AJCC stage        
 I + II 52 27 25   26 26  
 III + IV 36 10 26 0.024*a 29 7 0.004*a
T stage        
 T1 + T2 9 7 2   6 3  
 T3 + T4 79 30 49 0.032*b 49 30 1.000b
N stage        
 N0 54 30 24   29 25  
 N1 + N2 34 7 27 0.001*a 26 8 0.032*a
M stage        
 M0 86 37 49   53 33  
 M1 2 0 2 0.507b 2 0 0.526b
Differentiation        
 Well + Moderate 78 35 43   51 27  
 Poor 10 2 8 0.182b 4 6 0.167b
Vascular invasion        
 No 84 37 47   51 33  
 Yes 4 0 4 0.135b 4 0 0.292b
  1. Immunohistochemistry on tissue microarrays containing 88 paired CRC specimens was performed and more specific information was given in ‘Methods
  2. Key: *indicates P < 0.05. a Chi-square test. b Fisher’s exact test