Fig. 2

MEP1A knock-down inhibits colorectal cancer cell proliferation. Western blot analysis of MEP1A protein expression in stable knock-down Caco2 and LoVo cell-lines. Grayscale values were evaluated (n = 3, * p < 0.05) (a). Expression of proliferation-related genes was inhibited in MEP1A knock-down cells according to real-time PCR analysis (n = 3, * p < 0.05) (b). Effects of MEP1A knock-down on cell growth was evaluated by plate colony formation assays (c) and Cell Counting Kit-8 assays (d) (n = 3, * p < 0.05)