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Table 2 Univariate and multivariate analyses of the association between prognostic variables and disease-free survival in patients with cervical cancer

From: Prognostic significance of annexin A2 and annexin A4 expression in patients with cervical cancer

Risk factor Univariate Multivariate
Hazard ratio [95 % CI] P value Hazard ratio [95 % CI] P value
FIGO stage (> IIB) 2.44 [1.24–4.82] 0.010 1.38 [0.67–2.84] 0.381
Cell type (AD) 2.88 [1.62–5.14] <0.001 4.58 [2.48–8.45] <0.001
LN metastasis 4.13 [2.31–7.38] <0.001 3.82 [2.03–7.18] <0.001
Tumor size (>4 cm) 1.7 [0.92–3.15] 0.092 1 [0.51–1.95] 0.994
PM involvement 2.24 [1.05–4.81] 0.038 1.23 [0.55–2.76] 0.62
ANXA2+ 2.33 [1.28–4.25] 0.006 2.72 [1.41–5.27] 0.003
ANXA4+ 1.89 [1.04–3.41] 0.036 1.28 [0.64–2.56] 0.479
ANXA2+/ANXA4+ 4.21 [1.75–10.09] 0.001 2.69 [1.05–6.90] 0.039
  1. CI confidential interval, ANX annexin, FIGO International Federation of Gynecology and Obstetrics, AD adenocarcinoma, LN lymph node, PM parametrial