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Table 4 Prognostic factors predicting the efficacy of pemetrexed in patients with non-squamous non-small-cell lung cancer assessed using a multivariate Cox model

From: Predictive factors for a long-term response duration in non-squamous cell lung cancer patients treated with pemetrexed

Characteristics Hazard ratio (95 % CI) P-value
Never-smoker 1.997 (1.442–2.766) <0.001
Metastasis to intraabdomen 0.590 (0.410–0.847) 0.004
Number of metastatic lesion ≥2 0.668 (0.471–0.946) 0.023
Presence of EGFR mutation 0.520 (0.377–0.718) <0.001
  1. CI confidence interval; EGFR epidermal growth factor receptor