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Table 4 Prognostic factors predicting the efficacy of pemetrexed in patients with non-squamous non-small-cell lung cancer assessed using a multivariate Cox model

From: Predictive factors for a long-term response duration in non-squamous cell lung cancer patients treated with pemetrexed

Characteristics

Hazard ratio (95 % CI)

P-value

Never-smoker

1.997 (1.442–2.766)

<0.001

Metastasis to intraabdomen

0.590 (0.410–0.847)

0.004

Number of metastatic lesion ≥2

0.668 (0.471–0.946)

0.023

Presence of EGFR mutation

0.520 (0.377–0.718)

<0.001

  1. CI confidence interval; EGFR epidermal growth factor receptor