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Fig. 2 | BMC Cancer

Fig. 2

From: Systematic drug screening reveals specific vulnerabilities and co-resistance patterns in endocrine-resistant breast cancer

Fig. 2

Tamoxifen-resistant cells display distinct drug response profiles. a Hierarchical clustering and heat map visualization of the drug sensitivity score (DSS) differences of each resistant/parental cell line pair. Red (positive DSS difference) represents sensitivity and blue (negative DSS difference) co-resistance. Drugs with DSS difference < 5 in all of the comparisons were omitted. Black lines in the color bar highlight the cutoff (5, −5). b Tamoxifen-resistant clones derived from same parental cells display distinct drug response profiles. Venn diagrams show overlap of drugs that the cells become sensitive or co-resistant towards. Drugs with DSS difference < 5 were omitted

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