|
Stage
|
|
Stage IIB/C
|
2.15
|
(2.07, 2.24)
|
<.0001
|
1.70
|
(1.62, 1.78)
|
<.0001
|
|
Stage IIIA
|
1.00
|
–
|
–
|
1.00
|
–
|
–
|
|
Age
|
|
18–49
|
1.00
|
–
|
–
|
1.00
|
–
|
–
|
|
50–64
|
1.30
|
(1.17, 1.45)
|
<.0001
|
1.41
|
(1.22, 1.63)
|
<.0001
|
|
65–74
|
2.23
|
(2.02, 2.48)
|
<.0001
|
2.48
|
(2.16, 2.86)
|
<.0001
|
|
75 and more
|
4.86
|
(4.41, 5.37)
|
<.0001
|
5.12
|
(4.47, 5.87)
|
<.0001
|
|
Race/ Ethnicity
|
|
White
|
1.00
|
–
|
–
|
1.00
|
–
|
–
|
|
Black
|
0.96
|
(0.91, 1.02)
|
0.19
|
1.06
|
(0.98, 1.14)
|
0.14
|
|
American Indian, Aleutian, or Eskimo
|
0.90
|
(0.61, 1.33)
|
0.60
|
0.93
|
(0.58, 1.47)
|
0.75
|
|
Asian or Pacific Islander
|
0.55
|
(0.47, 0.64)
|
<.0001
|
0.62
|
(0.50, 0.75)
|
<.0001
|
|
Other
|
0.63
|
(0.46, 0.87)
|
0.005
|
0.64
|
(0.41, 0.99)
|
0.05
|
|
Facility Type
|
|
Community cancer program
|
1.39
|
(1.31, 1.48)
|
<.0001
|
1.40
|
(1.30, 1.52)
|
<.0001
|
|
Comprehensive community cancer center
|
1.21
|
(1.16, 1.26)
|
<.0001
|
1.24
|
(1.17, 1.31)
|
<.0001
|
|
Academic research program
|
1.00
|
–
|
–
|
1.00
|
–
|
–
|
|
Facility Location
|
|
New England
|
1.08
|
(0.99, 1.18)
|
0.10
|
0.94
|
(0.84, 1.06)
|
0.32
|
|
Mid Atlantic
|
1.07
|
(0.99, 1.16)
|
0.07
|
0.98
|
(0.89, 1.08)
|
0.68
|
|
South Atlantic
|
1.06
|
(0.99, 1.13)
|
0.12
|
1.00
|
(0.92, 1.09)
|
0.98
|
|
East North Central
|
1.10
|
(1.03, 1.18)
|
0.008
|
1.04
|
(0.95, 1.14)
|
0.39
|
|
East South Central
|
1.09
|
(0.998, 1.20)
|
0.05
|
1.08
|
(0.97, 1.21)
|
0.16
|
|
West North Central
|
1.10
|
(1.005, 1.19)
|
0.04
|
1.04
|
(0.94, 1.16)
|
0.43
|
|
West South Central
|
1.01
|
(0.92, 1.11)
|
0.80
|
0.99
|
(0.89, 1.11)
|
0.84
|
|
Mountain
|
0.93
|
(0.83, 1.04)
|
0.20
|
0.87
|
(0.75, 1.01)
|
0.06
|
|
Pacific
|
1.00
|
–
|
–
|
1.00
|
–
|
–
|
|
Urban/Rural Location
|
|
Metro ≥1 million
|
1.00
|
–
|
–
|
1.00
|
–
|
–
|
|
Metro 250 k to 1 million
|
1.07
|
(1.02, 1.12)
|
0.008
|
1.09
|
(1.03, 1.15)
|
0.004
|
|
Urban <250 k
|
1.07
|
(1.004, 1.14)
|
0.04
|
1.06
|
(0.98, 1.14)
|
0.17
|
|
Urban ≥ 20 k adjacent metro
|
1.10
|
(1.002, 1.21)
|
0.046
|
1.10
|
(0.98, 1.24)
|
0.09
|
|
Urban ≥ 20 k not adjacent metro
|
1.04
|
(0.89, 1.22)
|
0.65
|
1.05
|
(0.87, 1.26)
|
0.63
|
|
Urban <20 k adjacent metro
|
1.13
|
(1.04, 1.23)
|
0.006
|
1.06
|
(0.95, 1.18)
|
0.30
|
|
Urban <20 k not adjacent metro
|
1.23
|
(1.10, 1.38)
|
0.0005
|
1.32
|
(1.15, 1.52)
|
0.0001
|
|
Rural <2500 adjacent metro
|
1.02
|
(0.85, 1.24)
|
0.81
|
0.88
|
(0.68, 1.14)
|
0.33
|
|
Rural <2500 not adjacent metro
|
1.12
|
(0.94, 1.33)
|
0.21
|
1.06
|
(0.85, 1.32)
|
0.58
|
|
Comorbidities
|
|
0
|
1.00
|
–
|
–
|
1.00
|
–
|
–
|
|
1
|
1.46
|
(1.40, 1.53)
|
<.0001
|
1.49
|
(1.42, 1.58)
|
<.0001
|
|
2
|
2.29
|
(2.16, 2.42)
|
<.0001
|
2.29
|
(2.13, 2.46)
|
<.0001
|
|
Primary Site
|
|
Cecum
|
1.00
|
–
|
–
|
1.00
|
–
|
–
|
|
Ascending Colon
|
0.96
|
(0.91, 1.02)
|
0.15
|
1.04
|
(0.97, 1.11)
|
0.30
|
|
Hepatic Flexure
|
0.97
|
(0.88, 1.07)
|
0.51
|
0.95
|
(0.84, 1.07)
|
0.39
|
|
Transverse Colon
|
1.07
|
(0.997, 1.14)
|
0.06
|
0.93
|
(0.85, 1.02)
|
0.11
|
|
Splenic Flexure
|
1.07
|
(0.96, 1.18)
|
0.23
|
0.90
|
(0.77, 1.04)
|
0.15
|
|
Descending Colon
|
0.85
|
(0.78, 0.93)
|
0.0003
|
0.85
|
(0.77, 0.95)
|
0.003
|
|
Sigmoid Colon
|
0.76
|
(0.72, 0.80)
|
<.0001
|
0.82
|
(0.77, 0.87)
|
<.0001
|
|
Overlapping Lesions
|
1.19
|
(1.03, 1.38)
|
0.02
|
0.80
|
(0.62, 1.03)
|
0.08
|
|
Not Otherwise Specified
|
1.14
|
(1.004, 1.29)
|
0.04
|
1.13
|
(0.95, 1.33)
|
0.17
|
|
Grade
|
|
Well differentiated
|
1.00
|
–
|
–
|
1.00
|
–
|
–
|
|
Moderately differentiated
|
1.09
|
(1.02, 1.16)
|
0.01
|
1.04
|
(0.96, 1.13)
|
0.37
|
|
Poorly differentiated
|
1.39
|
(1.29, 1.50)
|
<.0001
|
1.11
|
(1.01, 1.22)
|
0.03
|
|
Undifferentiated, anaplastic
|
1.74
|
(1.53, 1.97)
|
<.0001
|
1.23
|
(1.02, 1.48)
|
0.03
|
|
Surgical Margins
|
|
No residual tumor
|
1.00
|
–
|
–
|
1.00
|
–
|
–
|
|
With Residual tumor
|
1.91
|
(1.81, 2.02)
|
<.0001
|
1.24
|
(1.03, 1.49)
|
0.02
|
|
Readmission within 30 days of Surgery
|
|
Not readmitted
|
1.00
|
–
|
–
|
1.00
|
–
|
–
|
|
Readmitted
|
1.15
|
(1.08, 1.22)
|
<.0001
|
1.13
|
(1.05, 1.22)
|
0.002
|
|
Regional Lymph Nodes Examined
|
|
0–11
|
1.34
|
(1.29, 1.39)
|
<.0001
|
1.29
|
(1.23, 1.35)
|
<.0001
|
|
12–90
|
1.00
|
–
|
–
|
1.00
|
–
|
–
|
|
Chemotherapy
|
|
Yes
|
1.00
|
–
|
–
|
1.00
|
–
|
–
|
|
No
|
3.55
|
(3.41, 3.70)
|
<.0001
|
3.49
|
(3.32, 3.67)
|
<.0001
|
