Table 1 Selected baseline patient and disease characteristics
FAS population | |
|---|---|
Age (years): median (range) | 64 (25–91) |
Age (years): n (%) | |
< 65 | 343 (52.4) |
≥ 65 | 311 (47.6) |
BMI (Kg/m2) | 24 (14.1–49.1) |
ECOG Performance Status: n (%) | |
0 | 200 (30.7) |
1 | 383 (58.7) |
2 | 60 (9.2) |
3 | 9 (1.4) |
Missing | 2 |
Site of Primary tumour: n (%) | |
Colon | 445 (69.9) |
Rectum | 186 (29.9) |
Colon and rectum | 5 (0.2) |
Missing | 18 |
Timing of metastases: n (%) | |
Synchronous | 416 (65.6) |
Metachronous | 218 (34.4) |
missing | 20 |
Delay from initial diagnosis of metastases (months): median (range) | 31 (0.8–156.5) |
Delay from initial diagnosis of metastases (months): n (%) | |
< 18 | 134 (20.6) |
≥ 18 | 518 (79.4) |
Missing | 2 |
KRAS mutational status: n (%) | |
Wild | 291 (46.8) |
Mutated | 331 (53.2) |
Missing | 32 |
Initial dose of REG, mg/d, 3 w/4: n (%) | |
40 | 3 (0.5) |
80 | 39 (6) |
120 | 89 (13.6) |
160 | 522 (79.9) |
Missing | 1 |