From: Debate: adjuvant whole brain radiotherapy or not? More data is the wiser choice
Study Year of Publication Did trial complete? | Accrual Total /years | Histologies RT dose (Total Gray/#) | No of BMs | Median Overall Survival of all cohort (Months) | Did AWBRT increase intracranial control? | Did AWBRT decrease neurological death? | Adequate NCF Testing |
---|---|---|---|---|---|---|---|
Patchell 1998 [21] Complete | 96/8 | All 60 % lung 50.4/28 | Single | 11 | Yes | Yes | No |
132/4 | All 65 % lung 30/12 | 1–4 | 8 | Yes | No difference | No | |
Chang 2009 [14] Incomplete | 58/6 | All 55 % lung 30/10 | 1–3 | 9.2 | Yes | No difference | Yes |
Roos 2011 [22] Incomplete | 19/3 | All 30/10 | Single | NA | NA | NA | No |
Kocher 2011 [23] Complete | 359/12 | All 50 % lung 30/10 | 1–3 | 10.9 | Yes | Yes | No |