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Table 4 List of significantly deregulated (P < 0.05) miRNAs in clinical samples vs. the model system

From: Comparison of the miRNA profiles in HPV-positive and HPV-negative tonsillar tumors and a model system of human keratinocyte clones

Probe name

miRNA family

tHFK vs. pHFKa

TT+ vs. NTb

Fold change

Fold change

hsa-miR-335-5p

mir-335

8.361

2.378

hsa-miR-579-3p

mir-548

7.921

1.945

hsa-miR-126-5p

mir-95

2.580

−4.049

Probe name

miRNA family

iHFK vs. pHFKa

TT- vs. NTb

Fold change

Fold change

hsa-miR-328-3p

mir-328

−22.020

−2.806

hsa-miR-34c-5p

mir-34

−16.419

4.851

hsa-miR-885-5p

mir-885

48.377

−3.725

  1. atHFK HPV-immortalized human foreskin keratinocyte clones, pHFK primary human foreskin keratinocyte clones, iHFK hTERT-immortalized human keratinocyte clones
  2. bTT+ HPV-positive tonsillar tumors, TT- HPV-negative tonsillar tumors