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Table 3 Subgroup analysis based on total taTME

From: Transanal total mesorectal excision (taTME) for rectal cancer: a systematic review and meta-analysis of oncological and perioperative outcomes compared with laparoscopic total mesorectal excision

Outcomes No. of patients No. of studies OR/WMD 95%CI Heterogeneity P value
taTME laTME   Low high I2 P value
Oncological outcomes         
Mactoscopic quality of mesorectum 119 119 4 2.03 0.99 4.16 11% 0.34 0.05
Harvested lymph nodes 169 219 5 −0.45 −1.98 1.08 0% 0.93 0.56
Circumferential resection margin 161 205 5 0.94 0.57 1.30 20% 0.29 <0.01*
Positive circumferential resectionmargin 119 119 4 0.31 0.08 1.18 0% 0.90 0.09
Distal resection margin 161 205 5 5.48 −0.17 11.13 73% <0.01 0.06
Positive distal resection margin 83 66 2 5.98 0.71 50.5 0% 0.92 0.10
Perioperative outcomes         
Operative time 144 194 4 −23.29 −45.60 -0.98 72% 0.01 0.04*
Conversion 144 194 4 0.31 0.08 1.18 0% 0.90 0.09
Hospital stay 144 194 4 −1.62 −3.62 0.38 74% 0.01 0.11
Intraoperative complications 144 194 4 0.94 0.30 3.01 0% 0.60 0.92
Postoperative complications 144 194 4 0.59 0.35 0.97 45% 0.14 0.04*
Anastomotic leakage 144 194 4 0.65 0.30 1.42 0% 0.66 0.28
Ileus 144 194 4 1.37 0.45 4.13 0% 0.49 0.58
Acute urinary retention 144 194 4 0.45 0.18 1.10 0% 0.81 0.08
Mobilization of splenic flexure 112 162 3 2.34 0.99 5.54 54% 0.12 0.05
Readmission 144 194 4 0.52 0.24 1.10 0% 0.57 0.09
  1. taTME transanal total mesorectal excision, laTME laparoscopic total mesorectal excision, OR odds ratios, WMD weighted mean difference, CI confidence interval; *P vaule with statistical significance