Transanal total mesorectal excision (taTME) for rectal cancer: a systematic review and meta-analysis of oncological and perioperative outcomes compared with laparoscopic total mesorectal excision

Table 1 Baseline characteristics of the included studies

Studies (NOS score)	Year	Country	Study design	Gender Male/Female	BMI Mean ± SD/median (range)		Age Mean ± SD/median (range)		ASA I + II/III + IV		Tumor location	Neoadjuvant treatment (Yes/No)		taTME type
Studies (NOS score)	Year	Country	Study design	taTME laTME	taTME	laTME	taTME	laTME	taTME	laTME		taTME	laTME
Velthuis [31] (3) 2014		Netherland	MCC	18/7 18/7	25 (20-36)	28 (21-34)	NR	NR	NR	NR	low/mid	25/0	25/0	Total
Kanso [27] (6)	2015	France	MCC	36/15 26/8	24 ± 4	24 ± 4	59 ± 11	59 ± 11	47/4	31/3	low	43/41^a	28/27^a	Partial
Hevia [28] (4)	2014	Spain	MCC	24/13 22/15	23.7 ± 3.6	25.1 ± 4.0	64.5 ± 11.8	69.5 ± 10.5	30/7	25/12	low/mid	28/9	23/14	Total
Chen [30] (4)	2015	Taiwan	MCC	38/12 76/24	24.2 ± 3.7	24.6 ± 3.1	57.3 ± 11.9	58.3 ± 11.3	33/17	69/31	low/mid	50/0	100/0	Total
Denost [32] (6) 2014		France	RCT	37/13 32/18	25 (17-33)	26 (18-38)	64 (39-82)	63 (31-90)	49/1	49/1	low	40/10	44/6	Partial
Perdawood [26] (4) 2015		Denmark	MCC	19/6 19/6	28 (18-46)	26 (19-38)	70 (54-76)	70 (49-84)	19/6	22/3	low/mid	7/18	4/21	Total
Angelis [29] (4) 2015		France	MCC	21/11 21/11	25.2 ± 3.5	24.5 ± 3.2	64.9 ± 10.0	67.2 ± 9.6	31/1	31/1	low/mid	27/5	23/9	Total

taTME transanal total mesorectal excision, laTME laparoscopic total mesorectal excision, BMI body mass index, ASA American Society of Anesthesiologists, MCC matched case control, RCT randomized controlled trial,
^aIn taTME group, 43 patients received neoadjuvant radiotherapy and 41 patients received neoadjuvant chemotherapy. In laTME group, 28 patients received neoadjcpuvant radiotherapy and 27 patients received neoadjuvant chemotherapy

ISSN: 1471-2407