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Table 2 Meta-analysis of p53 expression and clinicopathological features of EC

From: Prognostic significance of p53 expression in patients with esophageal cancer: a meta-analysis

Clinicopathological features N Cases Analytical model Pooled OR (95 % CI) P value Heterogeneity
I2 (%) P value
Tumor size (≤ 5 cm vs. > 5 cm) 4 1515 FEM 1.13 (0.92–1.40) 0.24 0 0.96
Tumor location (upper + middle vs. lower) 8 1205 FEM 0.91 (0.70–1.17) 0.45 0 0.80
Grade of differentiation (well + moderate vs. poor) 16 2328 FEM 1.10 (0.90–1.34) 0.35 17 0.26
Depth of invasion (T1/T2 vs. T3/T4) 13 2262 FEM 0.86 (0.71–10.3) 0.09 0 0.67
  1. N number of studies, FEM fixed-effect model