Table 2 Meta-analysis of p53 expression and clinicopathological features of EC
From: Prognostic significance of p53 expression in patients with esophageal cancer: a meta-analysis
Clinicopathological features | N | Cases | Analytical model | Pooled OR (95Â % CI) | P value | Heterogeneity | |
|---|---|---|---|---|---|---|---|
I2 (%) | P value | ||||||
Tumor size (≤ 5 cm vs. > 5 cm) | 4 | 1515 | FEM | 1.13 (0.92–1.40) | 0.24 | 0 | 0.96 |
Tumor location (upper + middle vs. lower) | 8 | 1205 | FEM | 0.91 (0.70–1.17) | 0.45 | 0 | 0.80 |
Grade of differentiation (well + moderate vs. poor) | 16 | 2328 | FEM | 1.10 (0.90–1.34) | 0.35 | 17 | 0.26 |
Depth of invasion (T1/T2 vs. T3/T4) | 13 | 2262 | FEM | 0.86 (0.71–10.3) | 0.09 | 0 | 0.67 |