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Table 3 Univariate analyses of factors independently prognostic of overall survival in the 307 patients with hepatocellular carcinoma

From: Optimal staging system for predicting the prognosis of patients with hepatocellular carcinoma in China: a retrospective study

Variable Coefficient SE P HR 95 % CI
Sex 0.39 0.28 0.156 1.48 0.86–2.54
Age −0.09 0.08 0.293 0.92 0.78–1.08
ECOG PS 0.74 0.10 0.000 2.10 1.74–2.54
Tumor size 0.15 0.02 0.000 1.16 1.12–1.21
Number of lesions 0.58 0.10 0.000 1.78 1.47–2.17
Lobar involvement 1.16 0.20 0.000 3.20 2.18–4.70
Tumor formation 0.70 0.11 0.000 2.01 1.63–2.49
Ascites 0.44 0.10 0.000 1.55 1.27–1.89
Total bilirubin 0.68 0.14 0.000 1.98 1.51–2.60
Albumin −0.10 0.02 0.000 0.91 0.88–0.94
Child-Pugh Grade 0.86 0.16 0.000 2.37 1.72–3.25
alpha-fetoprotein 0.72 0.18 0.000 2.05 1.43–2.94
hepatitis B virus −0.37 0.21 0.081 0.69 0.46–1.05
hepatitis C virus −0.55 0.59 0.347 0.58 0.18–1.82
Alcoholism 0.53 0.59 0.366 1.70 0.54–5.36
Other 0.42 0.23 0.066 1.53 0.97–2.39
Lymph node metastasis 0.81 0.21 0.000 2.26 1.48–3.43
Distant metastasis 1.37 0.22 0.000 3.93 2.56–6.05
Tumor thromboses 1.31 0.20 0.000 3.71 2.50–5.50
Portal hypertension 0.30 0.22 0.173 1.35 0.88–2.09
Cirrhosis −0.80 0.18 0.000 0.45 0.31–0.64
Vascular/organ invasion      
 Portal/hepatic vein 1.31 0.21 0.000 3.72 2.47–5.60
 Others 0.79 0.33 0.015 2.21 1.17–4.18