Characteristic | |
---|---|
Age, years | |
Mean ± SD | 55.43 ± 10.69 |
Range | 11–84 |
Sex, % | |
Male | 252 (82.1) |
Female | 55 (17.9) |
ECOG PS, % | |
0 | 100 (32.6) |
1 | 146 (47.6) |
2 | 44 (14.3) |
3 | 16 (5.2) |
4 | 1 (0.3) |
Etiology, % | |
HBV | 239 (77.8) |
HCV | 7 (2.3) |
HBV + HCV | 2 (0.7) |
Alcoholism | 5 (1.6) |
Other | 54 (17.6) |
Child-Pugh Grade, % | |
A | 239 (77.9) |
B | 56 (18.2) |
C | 12 (3.9) |
Child-Pugh Score, % | |
5 | 176 (57.4) |
6 | 63 (20.5) |
7 | 36 (11.7) |
8 | 9 (2.9) |
9 | 11 (3.6) |
10 | 9 (2.9) |
11 | 3 (1.0) |
Hepatic encephalopathy, % | |
No | 307 (100.0) |
Yes | 0 (0) |
Ascites, % | |
No | 219 (71.4) |
Little | 56 (18.2) |
Middle | 24 (7.8) |
Large | 8 (2.6) |
Portal hypertension, % | |
No | 245 (79.8) |
Yes | 62 (20.2) |
Cirrhosis, % | |
No | 97 (31.6) |
Yes | 210 (68.4) |
Laboratory values, mean ± SD | |
Total bilirubin (μmol/l) | 24.55 ± 50.93 |
Albumin (g/l) | 38.53 ± 5.78 |
Prothrombin time (sec) | 0.19 ± 0.80 |
AFP (ng/ml), % | |
< 400 | 211 (68.7) |
≥ 400 | 96 (31.3) |
Tumor characteristics | |
Tumor size (mean ± SD, cm) | 6.18 ± 4.04 |
Number of lesions, % | |
1 | 200 (65.2) |
2–3 | 29 (9.4) |
≥ 4 | 78 (25.4) |
Lobar involvement, % | |
Unilobar | 164 (53.4) |
≥ bilobar | 143 (46.6) |
Tumor morphology, % | |
Uninodular | 147 (47.9) |
Multinodular | 77 (25.1) |
Massive, diffuse | 83 (27.0) |
Vascular and/or organ invasion, % | |
No | 235 (76.6) |
Portal/hepatic vein | 52 (16.9) |
Other vascular | 9 (2.9) |
Organ invasion | 11 (3.6) |
N, % | |
No | 252 (82.1) |
Yes | 55 (17.9) |
M, % | |
No | 278 (90.6) |
Yes | 29 (9.4) |
Tumor thrombosis, % | |
None | 247 (80.4) |
Portal stem vein | 26 (8.5) |
Inferior vena cava | 6 (1.9) |
Hepatic vein branches | 2 (0.7) |
Portal vein branches | 16 (5.2) |
Vessel | 3 (1.0) |
Hepatic duct | 2 (0.7) |
Inferior vena cava branches and Portal vein branches and/or Hepatic vein branches | 5 (1.6) |
Current outcomes, % | |
Dead | 120 (39.1) |
Alive | 187 (60.9) |
OS, mean ± SD, months | 12.08 ± 11.87 |