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Table 3 Multivariate COX Regression analysis on factors for OSCC survival

From: Foxp3 overexpression in tumor cells predicts poor survival in oral squamous cell carcinoma

Characteristics 5-years OS rate 5-year RFS rate
  HR (95 % CI) P Value HR (95 % CI) P Value
T Stage
 T1 or T2 0.547 (0.331–0.904) 0.019* 1.188 (0.483–2.923) 0.707
 T3 or T4 Reference   Reference  
N Stage
 N0 0.238 (0.143–0.398) 0.000*** 0.614 (0.280–1.347) 0.223
 N1-N3 Reference   Reference  
Clinical Stage
 I-II 2.503 (1.348–4.649) 0.004** 2.249 (0.865–5.852) 0.097
 III-IV Reference   Reference  
Foxp3 Staining Value
 1 0.197 (0.123–0.315) 0.000*** 0.451 (0.239–0.849) 0.014*
 2 0.271 (0.174–0.422) 0.000*** 0.371 (0.192–0.714) 0.003**
 3 Reference   Reference  
  1. Abbreviations: OS overall survival, RFS, relapse free survival, HR hazard ratio, 95 % CI 95 % confidence interval
  2. P value was determined using Cox proportional-hazards model. *,P<0.05;**, P<0.01;***, P<0.001