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Table 3 Multivariate COX Regression analysis on factors for OSCC survival

From: Foxp3 overexpression in tumor cells predicts poor survival in oral squamous cell carcinoma

Characteristics

5-years OS rate

5-year RFS rate

 

HR (95 % CI)

P Value

HR (95 % CI)

P Value

T Stage

 T1 or T2

0.547 (0.331–0.904)

0.019*

1.188 (0.483–2.923)

0.707

 T3 or T4

Reference

 

Reference

 

N Stage

 N0

0.238 (0.143–0.398)

0.000***

0.614 (0.280–1.347)

0.223

 N1-N3

Reference

 

Reference

 

Clinical Stage

 I-II

2.503 (1.348–4.649)

0.004**

2.249 (0.865–5.852)

0.097

 III-IV

Reference

 

Reference

 

Foxp3 Staining Value

 1

0.197 (0.123–0.315)

0.000***

0.451 (0.239–0.849)

0.014*

 2

0.271 (0.174–0.422)

0.000***

0.371 (0.192–0.714)

0.003**

 3

Reference

 

Reference

 
  1. Abbreviations: OS overall survival, RFS, relapse free survival, HR hazard ratio, 95 % CI 95 % confidence interval
  2. P value was determined using Cox proportional-hazards model. *,P<0.05;**, P<0.01;***, P<0.001