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Table 3 Multivariable analysis of overall survival in 1435 patients according to clinicopathological variables

From: Prognostic and predictive significance of tumor length in patients with esophageal squamous cell carcinoma undergoing radical resection

  Categorical tumor length Continuous tumor length
Variable HR 95 % CI P value HR 95 % CI P value
Age 1.011 1.002–1.019 0.014 1.010 1.002–1.019 0.015
Male (reference) 1   0.371    
Female 0.896 0.706–1.139   0.908 0.715–1.155 0.342
Upper tumor (reference) 1      
Middle tumor 1.150 0.660–2.005 0.622 1.169 0.671–2.038 0.581
Lower tumor 1.113 0.637–1.945 0.708 1.130 0.647–1.974 0.668
G1 (reference) 1      
G2 1.503 1.153–1.959 0.003 1.516 1.163–1.976 0.002
G3 1.184 0.942–1.488 0.148 1.180 0.939–1.483 0.157
T1 (reference) 1      
T2 1.708 1.182–2.649 0.004 1.666 1.153–2.406 0.006
T3 2.140 1.521–3.009 <0.001 2.081 1.483–2.919 <0.001
T4 2.781 1.855–4.171 <0.001 2.691 1.797–4.028 <0.001
N0 (reference) 1      
N1 1.746 1.442–2.116 <0.001 1.716 1.416–2.078 <0.001
N2 2.974 2.422–3.652 <0.001 2.961 2.412–3.636 <0.001
N3 5.128 3.969–6.626 <0.001 5.091 3.939–6.580 <0.001
Vascular invasion 1.113 0.917–1.350 0.278 1.108 0.913–1.344 0.299
Perineural involvement 1.091 0.912–1.305 0.343 1.098 0.918–1.314 0.307
Number of resected lymph nodes 0.987 0.980–0.994 <0.001 0.987 0.980–0.994 <0.001
Tumor length 1.201 1.032–1.403 0.018 1.064 1.026–1.103 <0.001