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Table 2 Univariable analysis of overall survival in 1435 patients according to clinicopathological variables

From: Prognostic and predictive significance of tumor length in patients with esophageal squamous cell carcinoma undergoing radical resection

Variable

HR

95 % CI

P value

(C-index) (%)

Age

1.007

0.998–1.015

0.118

52.2

Sex

   

51.6

 Male (reference)

1

   

 Female

0.766

0.608–0.966

0.025

 

Tumor location

   

53.2

 Upper (reference)

1

   

 Middle

1.318

0.758–2.292

0.328

 

 Lower

1.534

0.882–2.666

0.129

 

Differentiation

   

55.4

 G1 (reference)

1

   

 G2

2.094

1.622–2.703

<0.001

 

 G3

1.442

1.154–1.802

<0.001

 

T stage

   

60.5

 T1 (reference)

1

   

 T2

2.253

1.572–3.230

<0.001

 

 T3

3.499

2.545–4.809

<0.001

 

 T4

5.593

3.835–8.156

<0.001

 

N stage

   

67.1

 N0 (reference)

1

   

 N1

2.001

1.661–2.409

<0.001

 

 N2

3.640

3.007–4.406

<0.001

 

 N3

6.180

4.882–7.823

<0.001

 

Vascular invasion

   

51.5

 No (reference)

1

   

 Yes

1.224

1.001–1.482

0.038

 

Perineural involvement

   

53.8

 No (reference)

1

   

 Yes

1.595

1.345–1.891

<0.001

 

Number of resected lymph nodes

1.002

0.995–1.008

0.577

50.3

Tumor length

   

56.1

  ≤ 4.0 cm (reference)

1

   

  > 4.0 cm

1.582

1.368–1.830

<0.001

 

Tumor length*

1.121

1.088–1.155

<0.001

58.1

  1. *tumor length treated as a continuous variable