Table 1 Patient characteristics
From: Better survival in right-sided versus left-sided stage I - III colon cancer patients
Patient characteristics | |||||
|---|---|---|---|---|---|
Total | Right-sided carcinoma | Left-sided carcinoma | Pa | ||
N = 91,416 | N = 51,937 | N = 39,479 | |||
Tumor stage | Stage I | 25,482 (27.9 %) | 13,864 (26.7 %) | 11,618 (29.4 %) | <0.001 |
(AJCC 6th ed.) | Stage II | 33,323 (36.5 %) | 19,965 (38.4 %) | 13,358 (33.8 %) | |
Stage III | 32,611 (35.7 %) | 18,108 (34.9 %) | 14,503 (36.7 %) | ||
T-stage | T1 | 14,110 (15.4 %) | 6415 (12.4 %) | 7695 (19.5 %) | <0.001 |
T2 | 15,873 (17.4 %) | 9580 (18.4 %) | 6293 (15.9 %) | ||
T3 | 51,416 (56.2 %) | 29,980 (57.7 %) | 21,436 (54.3 %) | ||
T4 | 10,017 (11.0 %) | 5962 (11.5 %) | 4055 (10.3 %) | ||
Number of positive | 0 | 58,805 (64.3 %) | 33,829 (65.1 %) | 24,976 (63.3 %) | <0.001 |
regional lymph nodes | 1 | 10,557 (11.5 %) | 5627 (10.8 %) | 4930 (12.5 %) | |
2–3 | 10,531 (11.5 %) | 5672 (10.9 %) | 4859 (12.3 %) | ||
4–6 | 6560 (7.2 %) | 3692 (7.1 %) | 2868 (7.3 %) | ||
7+ | 4963 (5.4 %) | 3117 (6.0 %) | 1846 (4.7 %) | ||
Number of retrieved | <12 lymph nodes | 24,256 (26.5 %) | 10,243 (19.7 %) | 14,013 (35.5 %) | <0.001 |
regional lymph nodes | 12–16 lymph nodes | 26,123 (28.6 %) | 14,917 (28.7 %) | 11,206 (28.4 %) | |
17+ lymph nodes | 41,037 (44.9 %) | 26,777 (51.6 %) | 14,260 (36.1 %) | ||
Grading | G1 | 8568 (9.4 %) | 4721 (9.1 %) | 3847 (9.7 %) | <0.001 |
G2 | 64,221 (70.3 %) | 34,812 (67.0 %) | 29,409 (74.5 %) | ||
G3 | 14,228 (15.6 %) | 9886 (19.0 %) | 4342 (11.0 %) | ||
G4 | 1490 (1.6 %) | 1099 (2.1 %) | 391 (1.0 %) | ||
Unknown | 2909 (3.2 %) | 1419 (2.7 %) | 1490 (3.8 %) | ||
Histology | Adenocarcinoma | 64,760 (70.8 %) | 35,637 (68.6 %) | 29,123 (73.8 %) | <0.001 |
Adeno-Ca in adenomatous polyp | 6791 (7.4 %) | 2885 (5.6 %) | 3906 (9.9 %) | ||
Adeno-Ca in villous adenoma | 2646 (2.9 %) | 1721 (3.3 %) | 925 (2.3 %) | ||
Adeno-Ca in tubulovillous adenoma | 8142 (8.9 %) | 4897 (9.4 %) | 3245 (8.2 %) | ||
Mucinous carcinoma | 9077 (9.9 %) | 6797 (13.1 %) | 2280 (5.8 %) | ||
CEA | C0-stage | 32,999 (36.1 %) | 18,679 (36.0 %) | 14,320 (36.3 %) | 0.185 |
C1-stage | 17,232 (18.9 %) | 9896 (19.1 %) | 7336 (18.6 %) | ||
Unknown/Borderline | 41,185 (45.1 %) | 23,362 (45.0 %) | 17,823 (45.1 %) | ||
Operation | Segmental resection | 36,201 (39.6 %) | 7750 (14.9 %) | 28,451 (72.1 %) | <0.001 |
Hemi/subtotal colectomy | 54,241 (59.3 %) | 43,777 (84.3 %) | 10,464 (26.5 %) | ||
Other | 974 (1.1 %) | 410 (0.8 %) | 564 (1.4 %) | ||
Year | 2004 to 2006 | 31,514 (34.5 %) | 17,703 (34.1 %) | 13,811 (35.0 %) | 0.005 |
2007 to 2009 | 31,314 (34.3 %) | 17,798 (34.3 %) | 13,516 (34.2 %) | ||
2010 to 2012 | 28,588 (31.3 %) | 16,436 (31.6 %) | 12,152 (30.8 %) | ||
Age | Up to 49 years | 8015 (8.8 %) | 3175 (6.1 %) | 4840 (12.3 %) | <0.001 |
50 to 64 years | 26,347 (28.8 %) | 12,344 (23.8 %) | 14,003 (35.5 %) | ||
65 to 79 years | 35,693 (39.0 %) | 21,435 (41.3 %) | 14,258 (36.1 %) | ||
80+ years | 21,361 (23.4 %) | 14,983 (28.8 %) | 6378 (16.2 %) | ||
Gender | Male | 43,981 (48.1 %) | 23,053 (44.4 %) | 20,928 (53.0 %) | <0.001 |
Female | 47,435 (51.9 %) | 28,884 (55.6 %) | 18,551 (47.0 %) | ||
Ethnicity | Caucasian | 72,937 (79.8 %) | 42,296 (81.4 %) | 30,641 (77.6 %) | <0.001 |
African-American | 10,572 (11.6 %) | 6286 (12.1 %) | 4286 (10.9 %) | ||
Other/Unknown | 7907 (8.6 %) | 3355 (6.5 %) | 4552 (11.5 %) | ||
Marital status | Married | 49,901 (54.6 %) | 27,219 (52.4 %) | 22,682 (57.5 %) | <0.001 |
Single | 11,581 (12.7 %) | 6120 (11.8 %) | 5461 (13.8 %) | ||
Widowed | 17,770 (19.4 %) | 11,835 (22.8 %) | 5935 (15.0 %) | ||
Other/Unknown | 12,164 (13.3 %) | 6763 (13.0 %) | 5401 (13.7 %) | ||