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Table 1 Clinical, histopathological and follow-up data for 42 HNSCC patients

From: Molecular analyses of unselected head and neck cancer cases demonstrates that human papillomavirus transcriptional activity is positively associated with survival and prognosis

Variable Number Percent
Site Larynx 16 38.1
Oropharynx 15 35.7
Hypopharynx 5 11.9
Oral cavity 4 9.5
Otherb 2 4.8
T stagea 1 8 19.0
2 10 23.8
3 10 23.8
4 13 30.1
n/a 1 2.4
N stagea 0 17 40.5
1 6 14.3
2 17 40.5
3 1 2.4
n/a 1 2.4
M stagea 0 40 92.9
1 0 4.8
X 2 2.4
Grade Well 0 0
Mod 27 64.3
Poor 12 28.6
n/a 3 7.1
  Surgery 27 64.2
Treatment RT 13 30.9
  CRT 2 4.7
Death Yes 9 21.4
No 33 78.6
Responsec Complete 29 69.0
Partial 4 9.5
None 7 16.7
n/a 2 4.8
Recurrence Yes 13 30.9
No 29 69.1
  1. T represents size or direct extent of the tumour, N the degree of lymph node spread and M the presence of metastases
  2. aPathological TNM staging; bTwo patients had primary SCC located in EAC; RT, primary radiotherapy; CRT, primary chemoradiotherapy; cPost-treatment clinical evaluation was undertaken at ~8-12 weeks [complete response is defined as the disappearance of all detectable disease at the primary site on visual inspection and/or imaging; partial response was defined as tumour reduction by >50 %]