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Table 3 Multivariate analysis of MYC expression and prognostic scoring systems for progression-free survival and overall survival in all patients with PCNS-DLBCL

From: MYC and BCL2 overexpression is associated with a higher class of Memorial Sloan-Kettering Cancer Center prognostic model and poor clinical outcome in primary diffuse large B-cell lymphoma of the central nervous system

 

PFS

OS

 

HR

95 % CI

P

 

HR

95 % CI

P

Age

0.989

0.949-1.032

0.614

Age

1.074

1.002–1.151

0.044

MYC ≥ 40

1.745

0.848–3.589

0.130

BCL2 ≥ 30

-a

-a

0.951

N-B, 2-3

2.243

1.072–4.693

0.032

N-B, 2-3

1.392

0.474–4.084

0.547

MSKCC, 2–3

2.635

0.502–13.827

0.252

MSKCC, 2–3

0.370

0.048–2.841

0.339

  1. Abbreviations: PFS progression-free survival, OS overall survival, HR hazard ratio, CI confidence interval, N-B Nottingham-Barcelona, MSKCC Memorial Sloan Kettering Cancer Center
  2. (avalues are not shown.)