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Table 1 Comparisons of clinical characteristics

From: Clinical characteristics and prognosis of 272 postterm choriocarcinoma patients at Peking Union Medical College Hospital: a retrospective cohort study

  1985–2006 2007–2014 P value
N = 123 N = 149
Mean age 30(22–57) 31(21–54) 0.25
Median gravidity 2(1–10) 2(1–8) 0.17
Median parity 1(1–9) 1(1–4) 0.56
Previous hydatidiform mole or invasive mole 21(17 %) 27(18 %) 0.82
Median interval from index pregnancy, months 7(0–216) 13(0–348) 0.002
Interval from index pregnancy <4 mo 47(38 %) 31(21 %) 0.002
Interval from index pregnancy >12 mo 36(29 %) 75(50 %) 0.000
Mean pretreatment β-hCG mIU/ml 119692 (6.5-3120000) 103554 (negative-2876010) 0.67
Pretreatment >400,000 β-hCG mIU/ml 5(4 %) 10(7 %) 0.34
Metastatic disease 98(80 %) 128(86 %) 0.17
Metastatic sites ≥2 38(31 %) 39(26 %) 0.39
Symptoms    
   Abnormal uterine bleeding 91(74 %) 111(74 %) 0.92
   Hemoptysis 14(11 %) 13(9 %) 0.47
   Central neural system symptoms 12(10 %) 4(3 %) 0.17
   Fetal death or stillbirth 3(2 %) 11(7 %) 0.07
Resistance to multiagent chemotherapy 49(40 %) 72(48 %) 0.16
Mean chemotherapy courses 8.5(1–27) 7.5(1–26) 0.44
Numbers of surgeries 75(61 %) 88(59 %) 0.75
Mean FIGO score 9.2(2–19) 9.4(2–22) 0.59
FIGO score >12 25(20 %) 31(21 %) 0.92
FIGO stage    
   I 24(20 %) 22(15 %) 0.30
   II 9(7 %) 0(0 %) n/aa
   III 66(54 %) 95(64 %) 0.09
   IV 24(19 %) 32(21 %) 0.69
  1. a chi-square test undefined