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Fig. 2 | BMC Cancer

Fig. 2

From: Systematic interactome mapping of acute lymphoblastic leukemia cancer gene products reveals EXT-1 tumor suppressor as a Notch1 and FBWX7 common interactor

Fig. 2

a Interactions between proteins mutated in ALL samples. Protein-protein interactions were extracted from three databases: IntAct, HPRD and BioGRID and only interactions reported with at least two publications, and detected by two experimental methods are represented in this map. b Co-occurrences of mutations in ALL samples. Nodes represent proteins associated with ALL, with an area proportional to the number of distinct mutations. Edges join pairs of interacting proteins for which mutations co-occur in the same samples. Edge widths are proportional to the number of samples with co-occurring mutations

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BMC Cancer

ISSN: 1471-2407

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