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Fig. 1 | BMC Cancer

Fig. 1

From: Systematic interactome mapping of acute lymphoblastic leukemia cancer gene products reveals EXT-1 tumor suppressor as a Notch1 and FBWX7 common interactor

Fig. 1

a Distribution of ALL census genes and other census genes according to number of mutations and number of samples and their distribution among driver genes. Red and bleu bars represent ALL census genes and other cancer census genes respectively (b) Mutations associated to ALL in cancer gene census. Frequency of mutations in the top 20 genes (36,909 ALL samples). The number and proportion of ALL samples in which gene mutations were detected are represented. c The 20 most frequently mutated genes in ALL samples; X-axis represents the proportion of samples where mutations were reported. d Number of distinct mutations per genes in ALL samples; X-axis represents the number of distinct mutations found in the coding sequences and Y-axis the top 20 genes with higher number of distinct mutations. e Occurrence of mutations per gene in ALL samples. Data source: COSMIC database

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