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Table 3 Characteristics of tumor lesions formed from MCF10AT1 cell implants in the nude mice. Classifications in order of tumor progression included mild intraductal papilloma (IDP), moderate IDP, florid IDP, ductal carcinoma in situ (DCIS), and invasive carcinoma

From: Methionine-restricted diet inhibits growth of MCF10AT1-derived mammary tumors by increasing cell cycle inhibitors in athymic nude mice

Lesions

CF

MR

Mean (%) SD

N

Mean (%) SD

N

Mild IDP

46.0 ± 19

15

49.4 ±15

18

Moderate IDP

24.7 ±13

15

26.7 ±11

18

Florid IDP

6.93 ±6.7

15

3.89 ±6

18

DCIS

1.07 ±2.8

15

0 ± 0 *

18

Invasive carcinoma

21.3 ±15

15

20.0 ±13

18

  1. * p ≤ 0.05