Skip to main content
Fig. 6 | BMC Cancer

Fig. 6

From: Methionine-restricted diet inhibits growth of MCF10AT1-derived mammary tumors by increasing cell cycle inhibitors in athymic nude mice

Fig. 6

Patients from the TCGA Invasive Breast Carcinoma study [26, 27] with altered P21 and P27 had a tendency to be Her2 negative and had decreased survival. a. Estrogen receptor (ER), progesterone receptor (PR), and ErbB2 receptor (Her2) status in the 11 patients with decreases in the CDKN1a (P21) gene expression and ER, PR, and Her2 status of the 21 patients with decreases in the CDKN1b (P27) gene expression. b. Survival curve of patients with decreases in cdkn1a or cdkn1b gene expression compared to the 526 breast invasive carcinoma patients with mRNA Agilent microarray data. A rapid decrease in overall survival occurs in patients with decreases in cdnk1a or cdnk1b gene expression when compared to all patients with cancer

Back to article page

BMC Cancer

ISSN: 1471-2407

Contact us