Fig. 5From: Methionine-restricted diet inhibits growth of MCF10AT1-derived mammary tumors by increasing cell cycle inhibitors in athymic nude miceReduced levels of proliferation were seen by 24 h in MDA-MB-231 and to a lesser degree in MCF10A cells. In both cell types, time had significant affect on proliferation. In MDA-MB-231 cells, time, diet, and the interaction of time and diet on proliferation were significantly affected by MRCD media, whereas in MCF10A cells only an interaction with time and MR affected proliferation. Data was normalized to cells grown in regular media at time 0 and analyzed using a two-way ANOVA with Sidak’s multiple comparisons. ****p ≤ 0.0001, ***p ≤ 0.001, ** p ≤ 0.01, * p ≤ 0.05Back to article page