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Fig. 3 | BMC Cancer

Fig. 3

From: Methionine-restricted diet inhibits growth of MCF10AT1-derived mammary tumors by increasing cell cycle inhibitors in athymic nude mice

Fig. 3

Increases in apoptosis and decreases in proliferation occur in mice on the MR diet when compared to mice on the CF diet. a, c are representative images of Ki67 positive staining in mammary tissue near the tumor. b, d represent images of cleaved caspase-3 (CC3) positive staining in the tissue. a, b are representative sections from mice on the MR diet and c, d are representative sections from mice on the CF diet. e and f quantify the Ki67 and cleaved caspase-3 stained tissue sections from 20 animals per treatment, respectively. Mann-Whitney unpaired one-tailed t-test was performed on the samples. * p ≤ 0.05, ** p ≤ 0.01

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