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Table 1 Analysis of the reproductive and sexual life style conventional risk factors for cervical cancer in study population

From: Risk allelic load in Th2 and Th3 cytokines genes as biomarker of susceptibility to HPV-16 positive cervical cancer: a case control study

Sociodemographic characteristics n (%) Controls/n (%) CC ORc (95 % CI)  
n = 200/200 Cervical cancer (CC) p valuea
Age of menarche (years)  
 <12 82 (41)/76 (38) 1 (reference)  
 ≥12 118 (56)/124 (62) 0.76 (0.47–1.22) 0.26
Age at first intercourse (years)  
 ≥18 114 (57)/50 (25) 1 (reference)  
 <18 86 (43)/150 (75) 5.64 (3.32–9.56) b 0.0001
Parity  
 ≤3 177 (88.5)/71 (35.5) 1 (reference)  
 >3 23 (11.5)/129 (64.5) 7.41 (4.23–12.98) b 0.0001
Number of lifetime sexual partners  
 <3 169 (84.5)/148 (74) 1 (reference)  
 4 a 9 28 (14)/50 (25) 2.27 (1.24–4.15) b 0.008
 >10 3 (1.5)/2 (1) 2.79 (0.42–18.41) 0.28
Contraceptive method  
 None 28 (14)/111 (55.5) 1 (reference)  
 Non hormonals 88 (44)/56 (28) 0.25 (0.139–0.458) 0.0001
 Hormonal methods 6 months-5 years 84 (42)/33 (16.5) 0.15 (0.08–0.29) b 0.0001
History of previous STD  
 None 109 (54.5)/144 (72) 1 (reference)  
 Herpes 5 (2.5)/2 (1) 0.4 (0.065–2.44) 0.32
 Chlamydia 1 (0.5)/1 (0.5) 0.46 (0.028–7.50) 0.58
 Candidiasis 33 (16.5)/1 (0.5) 0.02 (0.003–0.235) 0.001
 Vaginosis 33 (16.5)/49 (24.5) 1.32 (0.73–2.39) 0.34
 HPV 19 (9.5)/3 (1.5) 0.18 (0.04–0.69) 0.01
Cancer family history  
 No 176 (88)/158 (79) 1 (reference)  
 Yes 24 (12)/42 (21) 2.19 (1.15–4.16) b 0.01
Smoking history  
 No 155 (77.5)/125 (62.5) 1  
 Yes 45 (22.5)/75 (37.5) 2.15 (1.28–3.63) b 0.004
  1. Bold text denotes significant p values (p < 0.05)
  2. a p value for Kruskal-Wallis test
  3. bStatistically significant p values for trend (p < 0.05)
  4. cOdds Ratio adjusted by age