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Table 3 Major functional classification of differentially abundant proteins

From: Protein expression changes induced in a malignant melanoma cell line by the curcumin analogue compound D6

 

Stress response

 

mRNA processing/translation

 

Others

1

UBC [24] ↑

1

SNRPD3 [33] ↑

1

KRT1 [40] ↑

2

HSPE1 [22] ↑

2

GNB2L1 [36] ↑

2

LDHB [43] ↑

3

HSPA1/HSP70 [22] ↑

3

RPL24 [32] ↓

3

TUBA1B [41] ↑

4

DnaJ B 1 [22] ↑

4

RPL26 [32] ↓

4

HIST1H4A [42] ↑

5

RPS3 [28] ↑

5

HNRNPM [34] ↓

5

HIST1H2AC [42] ↓

6

HSPH1 [22] ↑

6

RPL17 [32] ↓

6

HIST1H2AB [42] ↓

7

YWHAE [31] ↑

7

SYNCRIP [35] ↓

7

HIST1H2AD [42] ↓

8

YWHAZ [31] ↑

8

RPS11 [32] ↓

  

9

HSPA1L [22] ↑

9

DDX17 [37] ↓

  

10

HSPA6 [22] ↑

10

RALY [38] ↓

  

11

HSPA7 (HSP90AA1) [22] ↑

11

BZW2 [39] ↓

  

12

HSPB1 [22] ↑

    

13

PPIB [29] ↓

    

14

H2AFX [26] ↓

    

15

PDIA4 [30] ↓

    

16

H2AFZ [27] ↓

    
  1. Proteins in the table are grouped according to their putative role in our model. Each protein is identified by the corresponding gene symbol. Up- or down-facing arrows indicates up- or down-regulated proteins, respectively