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Table 3 Major functional classification of differentially abundant proteins

From: Protein expression changes induced in a malignant melanoma cell line by the curcumin analogue compound D6

  Stress response   mRNA processing/translation   Others
1 UBC [24] ↑ 1 SNRPD3 [33] ↑ 1 KRT1 [40] ↑
2 HSPE1 [22] ↑ 2 GNB2L1 [36] ↑ 2 LDHB [43] ↑
3 HSPA1/HSP70 [22] ↑ 3 RPL24 [32] ↓ 3 TUBA1B [41] ↑
4 DnaJ B 1 [22] ↑ 4 RPL26 [32] ↓ 4 HIST1H4A [42] ↑
5 RPS3 [28] ↑ 5 HNRNPM [34] ↓ 5 HIST1H2AC [42] ↓
6 HSPH1 [22] ↑ 6 RPL17 [32] ↓ 6 HIST1H2AB [42] ↓
7 YWHAE [31] ↑ 7 SYNCRIP [35] ↓ 7 HIST1H2AD [42] ↓
8 YWHAZ [31] ↑ 8 RPS11 [32] ↓   
9 HSPA1L [22] ↑ 9 DDX17 [37] ↓   
10 HSPA6 [22] ↑ 10 RALY [38] ↓   
11 HSPA7 (HSP90AA1) [22] ↑ 11 BZW2 [39] ↓   
12 HSPB1 [22] ↑     
13 PPIB [29] ↓     
14 H2AFX [26] ↓     
15 PDIA4 [30] ↓     
16 H2AFZ [27] ↓     
  1. Proteins in the table are grouped according to their putative role in our model. Each protein is identified by the corresponding gene symbol. Up- or down-facing arrows indicates up- or down-regulated proteins, respectively