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Table 1 Upregulated proteins

From: Protein expression changes induced in a malignant melanoma cell line by the curcumin analogue compound D6

Accession Gene symbol Protein name Fold-change treated/control FDR
P0CG48 UBC Polyubiquitin-C 6.32 0.00000
P61604 HSPE1 10 kDa heat shock protein, mitochondrial 5.82 0.00001
P08107 HSPA1/HSP70 Heat shock 70 kDa protein 1A/1B 4.97 0.00007
P62318 SNRPD3 Small nuclear ribonucleoprotein Sm D3 4.20 0.00325
P25685 DNAJB1 DnaJ homolog subfamily B member 1 3.72 0.00706
P23396 RPS3 40S ribosomal protein S3 3.72 0.00325
Q92598 HSPH1 Heat shock protein 105 kDa 3.51 0.00080
P04264 KRT1 Keratin, type II cytoskeletal 1 3.42 0.04177
P62258 YWHAE 14-3-3 protein epsilon 3.38 0.03245
P63244 GNB2L1 Guanine nucleotide-binding protein subunit beta-2-like 1 3.05 0.04582
P63104 YWHAZ 14-3-3 protein zeta/delta 2.89 0.00730
P34931 HSPA1L Heat shock 70 kDa protein 1-like 2.82 0.00371
P07195 LDHB L-lactate dehydrogenase B chain 2.70 0.03245
P17066 HSPA6 Heat shock 70 kDa protein 6 2.58 0.02396
P68363 TUBA1B Tubulin alpha-1B chain 2.39 0.01570
P48741 HSPA7 Putative heat shock 70 kDa protein 7 2.36 0.04329
P04792 HSPB1 Heat shock protein beta-1 2.27 0.01149
P62805 HIST1H4A Histone H4 1.52 0.00054
  1. The table lists the proteins that showed to be upregulated (fold-change >1.3) in LB24Dagi MM cells after 24 h of 10 μM D6 treatments (FDR <0.05). Proteins modulated also at the gene expression level are shown in bold characters [10]