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Table 1 Upregulated proteins

From: Protein expression changes induced in a malignant melanoma cell line by the curcumin analogue compound D6

Accession

Gene symbol

Protein name

Fold-change treated/control

FDR

P0CG48

UBC

Polyubiquitin-C

6.32

0.00000

P61604

HSPE1

10 kDa heat shock protein, mitochondrial

5.82

0.00001

P08107

HSPA1/HSP70

Heat shock 70 kDa protein 1A/1B

4.97

0.00007

P62318

SNRPD3

Small nuclear ribonucleoprotein Sm D3

4.20

0.00325

P25685

DNAJB1

DnaJ homolog subfamily B member 1

3.72

0.00706

P23396

RPS3

40S ribosomal protein S3

3.72

0.00325

Q92598

HSPH1

Heat shock protein 105 kDa

3.51

0.00080

P04264

KRT1

Keratin, type II cytoskeletal 1

3.42

0.04177

P62258

YWHAE

14-3-3 protein epsilon

3.38

0.03245

P63244

GNB2L1

Guanine nucleotide-binding protein subunit beta-2-like 1

3.05

0.04582

P63104

YWHAZ

14-3-3 protein zeta/delta

2.89

0.00730

P34931

HSPA1L

Heat shock 70 kDa protein 1-like

2.82

0.00371

P07195

LDHB

L-lactate dehydrogenase B chain

2.70

0.03245

P17066

HSPA6

Heat shock 70 kDa protein 6

2.58

0.02396

P68363

TUBA1B

Tubulin alpha-1B chain

2.39

0.01570

P48741

HSPA7

Putative heat shock 70 kDa protein 7

2.36

0.04329

P04792

HSPB1

Heat shock protein beta-1

2.27

0.01149

P62805

HIST1H4A

Histone H4

1.52

0.00054

  1. The table lists the proteins that showed to be upregulated (fold-change >1.3) in LB24Dagi MM cells after 24 h of 10 μM D6 treatments (FDR <0.05). Proteins modulated also at the gene expression level are shown in bold characters [10]