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Table 2 Baseline characteristics by NLR

From: Pretreatment neutrophil-to-lymphocyte ratio is correlated with response to neoadjuvant chemotherapy as an independent prognostic indicator in breast cancer patients: a retrospective study

  

NLR

 

Characteristic

No. of patients

<2.1 (n = 111)

≥2.1 (n = 104)

P

No. (%)

No. (%)

Age (yr)a

215

45.4 ± 9.3

47.5 ± 10.2

NS

cTb

215

  

<0.05

 1

 

2 (1.8)

1 (1.0)

 

 2

 

66 (59.5)

42 (40.4)

 

 3

 

36 (32.4)

48 (46.2)

 

 4

 

7 (6.3)

13 (12.5)

 

cNb

215

  

NS

  0

 

25 (22.5)

21 (20.2)

 

  1

 

61 (55.0)

47 (45.2)

 

  2

 

18 (16.2)

25 (24.0)

 

  3

 

7 (6.3)

11 (10.6)

 

cTNMb

215

  

<0.05

  0

 

0(0.0)

0(0.0)

 

  1

 

0(0.0)

0(0.0)

 

  2

 

67 (60.4)

41 (39.4)

 

  3

 

44 (39.6)

63 (60.6)

 

HG

215

  

NS

  1

 

36 (32.4)

32 (30.8)

 

  2

 

51 (45.9)

42 (40.4)

 

  3

 

24 (21.6)

30 (28.8)

 

ER

215

  

NS

  -

 

27 (24.3)

38 (36.5)

 

  +

 

84 (75.7)

66 (63.5)

 

PR

215

  

NS

  -

 

39 (35.1)

34 (32.7)

 

  +

 

72 (64.9)

70 (67.3)

 

HER2

215

  

NS

  -

 

68 (61.3)

70 (67.3)

 

  +

 

43 (38.7)

34 (32.7)

 

ER+ and/or PR+

174

93 (83.8)

81 (77.9)

NS

ER− PR−

41

18 (16.2)

23 (22.1)

 

Molecular subtype

215

  

NS

  Luminal A

 

62 (55.9)

58 (55.8)

 

  Luminal B

 

30 (27.0)

22 (21.2)

 

  HER2-enriched

 

12 (10.8)

13 (12.5)

 

  Triple-negative

 

7 (6.3)

11 (10.6)

 

CRP (before NAC)

215

1.5 (0.5, 4.8)

2.9 (0.9, 6.7)

<0.05

Relapse (local and distant)

   

<0.05

  No

176

98 (88.3)

78 (75.0)

 

  Yes

39

13 (11.7)

26 (25.0)

 

Death

   

<0.05

  No

183

102 (91.9)

81 (77.9)

 

  Yes

32

9 (8.1)

23 (22.1)

 
  1. aMean ± SD. bcT, cN, cTNM are clinical stages before NAC