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Fig. 3 | BMC Cancer

Fig. 3

From: MicroRNA-663a is downregulated in non-small cell lung cancer and inhibits proliferation and invasion by targeting JunD

Fig. 3

miR-663a regulates mRNA and protein expression of cyclin D1, cyclin E and MMP9. a Western blot showed that cyclin D1, cyclin E and MMP9 protein levels of H460 cells treated with miR-663a mimic were lower than those of control. cyclin D1, cyclin E, MMP9 protein levels of H1299 cells treated with miR-663a inhibitor were higher than those of control. Protein quantification of protein was shown for cyclin D1, cyclin E and MMP9 in these two cell lines. b Realtime PCR analysis showed that cyclin D1, cyclin E, MMP9 mRNA expression of H460 cells treated with miR-663a mimic were lower than those of cells transfected with control. cyclin D1, cyclin E, MMP9 mRNA expression of H1299 cells treated with miR-663a inhibitor were higher than those of cells transfected with control. Experiments were repeated in triplicate. Error bars indicate standard deviation

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BMC Cancer

ISSN: 1471-2407

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