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Table 2 Correlation of HAS1 and HAS2 with clinical and histopathological factors

From: Decreased expression of hyaluronan synthase 1 and 2 associates with poor prognosis in cutaneous melanoma

Variable HAS1 Coverage HAS1 Intensity HAS2 Coverage HAS2 Intensity
Stage p = 0.006 ns ns p = 0.047
pT1, pT4 or pN1-     
Melanoma related death p = 0.007 ns p = 0.001 p = 0.016
Recurrence p = 0.021 ns p = 0.007 ns
Regional recurrence p = 0.006 p = 0.023 p = 0.007 ns
Distant recurrence p = 0.012 ns p = 0.001 p = 0.004
Genre ns ns ns ns
Age ns ns ns ns
Ulceration ns ns ns ns
TIL (low / moderate / high) ns ns p = 0.036 p = 0.040
Mitotic count (mitosis/mm2) ns ns ns p = 0.018
Horizontal diameter of melanoma (mm) ns ns p = 0.002 p =0.042
Growth type     
Nodular ns ns ns p = 0.001
  1. Stage = pT1, pT4 or pN1-. TIL = tumor-infiltrating lymphocytes (evaluated either low, moderate or high amount). Mitosis = mitosis/mm2, horizontal tumor diameter (mm)