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Fig. 6 | BMC Cancer

Fig. 6

From: Heme oxygenase is not involved in the anti-proliferative effects of statins on pancreatic cancer cells

Fig. 6

Effect of hemin and cerivastatin on ROS production and apoptosis in PA-TU-8902 and BxPC-3 pancreatic cancer cells. The effects of hemin (30 μM), cerivastatin (12 μM) and their combination on apoptosis in a) PA-TU-8902 and b) BxPC-3, and ROS production in c) PA-TU-8902 and d) BxPC-3 were measured after 48 h of treatment. An+/PI- represents cells in early apoptosis, An + and/or PI+ represents cells in late apoptosis or already dead. *p < 0.05, **p < 0.01, ***p < 0.0001 vs. control cells. CON, control cells; CER, cerivastatin

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