Fig. 3

Effects of hemin and statins on proliferation of pancreatic cancer cells. The effects of hemin (30 μM), cerivastatin (12 μM), fluvastatin (12 μM) and pravastatin (12 μM) and their combination with hemin were measured in a) PA-TU-8902, b) MiaPaCa-2, and c) BxPC-3 after 48 h of treatment using CellTiter-Glo test. *p < 0.01, **p < 0.0001 vs. control cells, #p < 0.01 vs. hemin CON, control cells; CER, cerivastatin; FLU, fluvastatin; PRA, pravastatin