Fig. 1

Anti-proliferative effect of statins on pancreatic cancer cells. The effect of simvastatin, cerivastatin, fluvastatin, lovastatin and pravastatin on cell proliferation was measured using MTT test in a) PA-TU-8902, b) MiaPaCa-2, and c) BxPC-3 after 48 h of treatment. Statin concentration = 12 μM *p < 0.01, **p < 0.0001 vs. control cells. CON, control cells; SIM, simvastatin; CER, cerivastatin; FLU, fluvastatin; LOV, lovastatin; PRA, pravastatin